A Non-Scientist's Intro to the Endocannabinoid System | Easy as A B C

Living in Minnesota, cannabis is recreationally illegal, but I believe on it’s way as the rest of our nation leads by example in legalization. Case in point, states applying cannabis use for opiate addictions are seeing 30%+ in a reduction of overdoses and opiate abuse.

Medically, cannabis brings hundreds of health benefits to both the body and the mind. Studies share it can help quell anxiety, relieve pain, and decrease epileptic symptoms, and these are just a few possible cannabis perks. Cannabis isn’t for everyone, and it’s not a miracle drug. As a avid cannabis coach, the rewards is different for every consumer.

How Cannabis Effects on The Human Body

The reason why cannabis can seem like a magical healer has to do with the endocannabinoid system. This system is present in all mammals. I love the beautiful story of how we’ve existed and relied on plant medicine rapport for ions and ions.

Alright, let’s awaken beauty, here’s how the ECS works, and why it plays a major part in the way we process cannabis and CBD.

What is the Endocannabinoid System?

You’re probably familiar with the different organ systems of the human body—the skeletal, muscular, and circulatory systems, to name a few—but you might be less aware of the endocannabinoid system, also known as the ECS. Its main function is to ensure homeostasis in the human body, meaning it exists primarily to maintain balance. It was discovered in 1992 when researchers discovered that the body creates its own cannabinoid, called anandamide, which is the Sanskrit word for bliss. The ECS is made up of three different components: endocannabinoids, cannabinoid receptors, and enzymes.

Let’s dive into these biological relationships!

the first discovered naturally-occurring endocannabinoid, which attaches to the same mammalian brain-cell receptors as THC. Its name is derived from the Sanskrit word for “bliss.”

what makes the endocannabinoid system one of the most important systems in the body because its main function is to maintain balance and homeostasis.

​sit on the surface of cells and transmit information to the inside of the cell, kick-starting the appropriate cellular response.

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A Non-Scientist's Intro to the Endocannabinoid System

Endocannabinoids

Cannabinoids are chemical compounds that play a major part in ensuring that the body’s central nervous system functions correctly.

There are three different kinds: endocannabinoids, which are created naturally by our bodies; phytocannabinoids, which mimic the ones in our bodies and are also found in cannabis plants; and synthetic cannabinoids, which are lab-created. Endocannabinoids are known as our “Bliss Molecule,” representing anandamide, and 2-arachidonoylglycerol. These two receptors either bond or send a messaging signal to the ECS, signaling to the cells just what they need to do. (Best boss in town)!

Cannabinoid Receptors

The next aspects of the ECS are the cannabinoid receptors, otherwise known as CB1 and CB2. Many refer to these as the “locks” where the endocannabinoids are the “key.” CB1 receptors are located in the brain, particularly in the parts responsible for mental and physiological functions. CB2 is located throughout the immune system, peripheral nervous system (outside of the brain and spinal cord), and the digestive system. Signaling these receptors allows the body to regulate many important functions, such as digestion, appetite, immunity, inflammation, mood, sleep, fertility, memory, and more.

Enzymes

Once the messages are sent between the endocannabinoids and the receptors, enzymes enter the picture and break these messages down before the party gets out of sync and intuitively transitions the moving parts.

Enter Cannabis!

When we use cannabis and/or CBD, we’re inviting phytocannabinoids into our body, which mimic our natural endocannabinoids to help preserve homeostasis. If for some reason your body is out of whack and cannot bring itself to balance, this is where cannabis proves itself beneficial. It’s know that 20% of society has a ECS Genetic Deficiency, while sub-immune ailments are also now being linked to a sub-par ECS system.

It’s kinda like an adaptogen. Let’s say you’re in pain: cannabinoids will help modulate that pain; if you need help stimulating appetite, cannabinoids can make you hungry. Even beyond the ECS, cannabis effects multiple physiological processes and does what it is needed to get things on the right track.

So that’s the long and short of the KEY PLAYERS between cannabis, CBD and our biology!

Follow along @beautyecology and connect to our Youtube channel to listen up while ya work!

Is Cannabis (CBD) Safe with Other Medications?

Are you currently thinking about taking CBD, but too nervous to because you're on a medication?   This subject matter comes up a lot, so I thought I'd break it down quickly to bring clarity to the nuances of CBD and drug interactions. 

Cannabidiol (CBD) is one of over 80 phytocannabinoids, or chemical compounds, produced by the cannabis plant.  Starting off, Cannabidiol (CBD) itself has no dangerous interactions with other drugs you may be taking.

The breakdown of CBD and Drug interactions is all in the PATHWAY.

How?   Lets dig in!

Just How Safe is CBD Oil?

Hemp’s cannabidiol continues to be one of the safest alternative therapies on the market. In a review published in 2017, entitled “An Update on Safety and Side Effects of Cannabidiol,” a Clinical Data author asserted: "In general CBD is the most commonly reported side effects that are relatively rare and mild.   

Comparably to the laundry list of drug symptoms - CBD has a short list of that few experience such as feeling tired or changes in appetite. Everyone has various levels of sensitivities, let alone the importance of making sure you’re buying high quality CBD!

How Does Your Body Metabolize CBD?

It’s important to understand how the human body processes CBD.   Essentially, our body breaks CBD down through metabolization, just like other oral drugs by entering the digestive tract.  Here, they absorbs through the stomach lining into the hepatic portal system. This system is a vital system of veins connecting the stomach to the liver, and also acts as one of the body’s filter systems.

Once CBD enters the liver, it soaks up the P450 enzyme processing capability, inhibiting its ability to break down any other hepatically metabolized drugs. The cytochrome P450-complex enzyme becomes entirely preoccupied with processing CBD, with little to no room to break down other compounds also awaiting metabolization.

While the P450 enzyme interact with CBD, the body virtually stops processing any other pharmaceuticals with the same metabolic pathway. Interestingly, it's not the only P450 inhibitor to worry about.

Grapefruit Too?

Yup, something as natural and nourishing as a grapefruit comes with a similar warning about possible drug interaction. Physicians have long advised their patients to steer clear of grapefruit when taking certain medications.

If you do wish to pursue CBD as a co-therapy to other drugs, consider seeking medical advice and adjust dosages of any medications only on the recommendation of a doctor.

On the FLIP side, there is also a positive benefit to CBD hemp oil interaction with the P450 enzyme. Once we can make it proven through more robust studies, patients may be able to reduce their dose of other medications if CBD substantially increases the expected potency.

What Drugs Could CBD Interact With?

All drugs mainly metabolized by the liver pose a risk for adverse CBD drug interaction. Considering that 60 percent of clinically prescribed medication is metabolized in the liver via the P450 enzyme, it's not feasible to list them all here. Some of the most common types of medications which may trigger CBD hemp oil interactions include:

• HIV Antivirals

• Steroids

• Benzodiazepines

• Antihistamines

• Calcium Channel Blockers

• Fentanyl

• Macrolide Antibiotics

Cannabidiol (CBD) itself has no dangerous interactions, but it may interact with other drugs you may be taking according to medical journals.   Here's a list of possible drug interactions.

Why Does CYP450 Matter?

In order to determine the appropriate dosages of medications, doctors make calculations using the average amount of time it takes for various drugs and medications to be processed through the cytochrome P450 system.

If only one drug is being processed, and the system is generally healthy, these averages provide accurate dosage information.

However, certain substances have the ability to affect processing times within this system, making drugs metabolize faster or slower than they would on their own.

Similarly, if the cytochrome P450 system is unhealthy due to problems with the liver or other pre-existing conditions, drugs may not metabolize as they should.

Caffeine and CBD

Caffeine is the world’s most famous and commonly consumed psychoactive drug. Who doesn’t ingest even a little from time to time?

CBD oil is rapidly gaining ground on coffee in terms of popularity and so it only makes sense that people would start combining the two.

As it turns out, the two substances go very well together!

Caffeine is molecularly very similar to adenosine, a compound produced in our bodies that activates the A2a receptor. Caffeine binds to the A2a receptors, inhibiting the reuptake of adenosine.

When adenosine binds to the A2a receptor, the result is what is commonly known as the ‘rest and digest’ effect. Consequently, blocking adenosine from binding results in vasodilation, which increases clarity and alertness.

CBD oil is also a partial agonist of the A2a receptor; so the theory goes that by combining caffeine and CBD, adenosine is blocked across the board, resulting in not only more stimulation, but reduced anxiety (due to CBD’s effects on other neurotransmitters systems).

It is worth noting that these effects depend on the serving size of the CBD. High amounts of CBD are more likely to cause drowsiness and sedation.

Additionally, caffeine is metabolized by a CYP450 enzyme, specifically CYP1A2. As CBD inhibits the CYP450 enzyme system, a slowed excretion rate of caffeine will occur. This can mean the effects of the caffeine will be more prolonged and drawn out. The can be both good and bad!

On the bright side, CBD oil and caffeine together will cause the boost from your morning cup of coffee to last all day instead of just a few hours. On the downside, it’s easy to overdo it and end up wide-eyed in bed when you are trying to go to sleep.

Considering this information, again, it is best to be mindful and cautious when mixing caffeine and CBD.

Can CBD Oil Be Addictive?

One of the most common questions we get is: Can I get addicted to CBD oil? The answer depends on what you mean by “addicted.”

When looking at the chemical impacts of CBD oil, the answer is no. Cannabidiol is not physically addictive in the same way opiates, cocaine, alcohol, and other drugs can be. Also, CBD oil does not produce any physical withdrawal symptoms when you stop using it. In fact, CBD oil is currently being researched as a potential tool for minimizing the severe withdrawal from drugs like opiates.

But, having said that, human beings can get addicted to just about anything including exercise, music, sex, and food.

Because CBD oil can alter essential liver enzymes, it is crucial to do your research, talk to your physician, and figure out how to best consume CBD oil for your specific situation.

Information and education will be your most powerful weapons going forward.

How To Use CBD Oil

When taking cannabidiol, it is important to consume only the recommended serving size.  

Raising or lowering this amount may produce the opposite of the desired effect.

Keep in mind that some people may metabolize cannabidiol differently because of anomalies within the cytochrome P45O (CYP450) enzyme system. And depending on when you take your medications, you may find an unintended increase or decrease in CBD concentrations in your blood.

If you suspect that you are not metabolizing CBD oil as expected, ask your doctor to test your cytochrome P450 enzyme system before adjusting your dosage.

Resource:https://cbdoilreview.org/cbd-cannabidiol/cbd-p-450-enzyme/

Let’s review again.  Simply put…

When taking a dose of CBD, your body’s P450 enzymes will be temporarily inactive.   When enzymes are inactive, it becomes much harder for your body to process almost every drug out there.

This means:

Taking lots of CBD may increase the effects of any prescriptions drugs on your body. As they cannot be processed, the drugs will just stay in your body instead of being digested as they should.

The Good & Bad

The good side is that there may be a possibility reduce the amount of powerful prescription medications you take (speak to your physician before beginning or stopping medication). Regardless of what you take, it’s always best to put less artificial drugs into your body.

The bad side is just that you need to be careful. If you are taking CBD make sure to talk to a medical professional, and reduce the amount of prescription drugs you are taking.

So if you’re uber nervous, before adjusting any current prescriptions, or deciding to use CBD in conjunction with other drugs, always speak to a qualified medical professional.

From experience, many of my clients have been able to significantly lower the dosages of drugs they are using for a variety of ailments and symptoms.  This is the entire reason why CBD can benefit many - with the hope of reducing our use of drugs for everything from anxiety, insomnia, pain and headaches.

Making sure you’re purchasing very high quality CBD is a WHOLE OTHER SUBJECT.

Till next time!  Email me with any questions or concerns!  Hello@beautyecology.com

EVOQ CBD CURING CONCENTRATES

Sources:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569602/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576600/

https://www.cpsbc.ca/files/pdf/Methadone-Medications-Cytochrome-P450-3A4.pdf

How CBD Interacts With Medicines

In a previous editorial, I address this topic more in depth, but to get the quick and easy explanation, it’s all rolled out here.

Let’s dig in!

Cannabidiol (CBD) itself has no dangerous interactions with other drugs you may be taking.

But there is one exception:
Full Spectrum CBD might indirectly affect other pharmaceuticals by increasing their strength. This is because CBD stops a certain particle in your body from working effectively.
The liver enzyme Cytochrome P450 is essential for your body. It metabolizes almost all the drugs we consumed. It breaks down the substances you put in your body, and turns them into simpler substances that your body actually knows how to use.
Because of how complicated most medicines are, this means Cytochrome P450 alone allows us to break down over 60% of prescribed medicines.

Sounds important right?

Now this is the issue:
If you take a large dose of CBD, your body’s P450 enzymes will be temporarily inactive.
When those enzymes are inactive, it becomes much harder for your body to process almost every drug out there.

This means:

Taking lots of CBD will greatly increase the effects of any prescriptions drugs on your body.
As they cannot be processed, the drugs will just stay in your body instead of being digested as they should.

What does this mean?
This is both good and bad:

• The good side is that there may be a possibility to reduce the amount of powerful prescription medications you take (speak to your physician before beginning or stopping medication). Regardless of what you take, it’s always best to put less artificial drugs into your body.

• The bad side is just that you need to be careful. If you are taking CBD make sure to talk to a medical professional and reduce the amount of prescription drugs you are taking.

Again:

Cannabidiol (CBD) itself has no dangerous interactions with other drugs you may be taking according to medical journals. (more information can be found projectcbd.org).

Here's a list of possible drug interactions on https://www.drugs.com/drug-interactions/cannabis.html

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How Your Skin’s Endocannabinoid System’s Changing the Game & Your Genes for Good

Inflammation no mo!

How CBD is Changing the Skincare Game & Your Genes for Good

Whether it's fighting free radicals, treating blemishes,  or reducing inflammation, the power of cannabinoids (CBD) are proving to be a key for treating a variety of skin concerns.

Researcher and buyer beware, there is a lot of confusion and misinformation out there because of all the red tape  and the plethora of unregulated “me too CBD companies.”

In a previous editorial, we explored the body’s endocannabinoid system which is often referred to as ECS. We discovered the key roles your ECS plays in your overall wellness and outlined how CBD engages to bring equilibrium to your brain and body.

Next, we move onto the ECS and your skin!

Being in the skin industry for over two decades, the new re-discoveries around our skin’s very own endocannabinoid system and its own receptor ecosystem findings is beyond exciting. It put me into re-formulation mode (watch for our relaunch 2019).

When out of balance, the skin’s endocannabinoid system results in pathological skin conditions such as: acne, accelerated aging, dermatitis, psoriasis and seborrhea to name but a few.

The Gut Connection to our Skin’s Immunity

It is well-documented that the gastrointestinal tract, which, like the skin, is one of the primary physical barriers of the immune system, has abundant cannabinoid receptor sites.

Now, research has shown that the skin also has an endocannabinoid system of its own, which helps to regulate the production of various hormones and proteins, including cytokine causes the skin to spike into inflammation), which is also involved in the immune response.

The skin’s endocannabinoid system also helps to regulate various cellular processes including proliferation, differentiation, and apoptosis or cell death. Thus, imbalance of this system is responsible for the occurrence of chronic skin conditions such as advanced aging, psoriasis and eczema, and developing targeted cannabinoid therapies may help to control the root of optimal skin health.

Many skin conditions are inflammatory in nature and the anti-inflammatory effects of cannabinoids on skin cells have been demonstrated. Both THC and CBD show anti-inflammatory effects.

What’s happening below the surface.  

Skin flare ups are common whether it’s acne, psoriasis or eczema because hormones like cortisol tell the glands in your skin to make oil, suppress your immune system and can cause an inflammatory response in the skin.  

Applying CBD topically is an effective method for introducing cannabinoids to the skin’s ECS for immediate absorption, and faster results.

Topical Application of CBD

Topical applications of Cannabidiol can penetrate as deep as one inch from the surface.  Imagine what our Evoq Nano infused CBD can influence at 1 billionth of the size! Topicals containing higher amounts of CBD (5 mg per application) can offer relief from physical pain, arthritis and rheumatism.

Communicating the Connection Points

Human tissues have at least two types of cannabinoid receptors, CB1 and CB2, each coupled with a protein. CB1 receptors are expressed predominantly at nerve terminals where they mediate inhibition of neurotransmitter release.

CB2 receptors are found mainly on immune cells, one of their roles being to modulate cytokine release.

Endogenous ligands for these receptors, endocannabinoids, also exist, and examples include the molecule anandamide. These discoveries have led to the development of CB1- and CB2-selective agonists and antagonists and of bioassays for characterizing such ligands. So in the future we can have much more targeted cannabinoid therapies.

Human skin cells or keratinocytes are part of the peripheral endocannabinoid system and showed a unique signaling mechanism of CB1 receptors, which may have important implications in epidermal differentiation and skin development.

How About Scalp and Hair Health?

Cannabinoid receptors have been found in even the smallest nerve fibers controlling hair follicles, and keratinocytes have also been shown to bind and metabolize anandamide, the most abundant endocannabinoid.  Plant cannabinoids Δ-9 tetrahydrocannabinol (THC), cannabidiol, cannabinol and cannabigerol (CBG) for their ability to inhibit the proliferation of a hyper-proliferating human keratinocyte cell line and for any involvement of cannabinoid receptors for ultimate hair health.  

In other research, published in The Federation of American Societies for Experimental Biology (FASEB) Journal, it was shown that cannabinoids produce lipids that can regulate skin conditions such as acne vulgaris, seborrhea and dry skin. They suggested further exploration of cannabinoids as “novel therapeutic tools" to treat dry scalp.   

In summary, we have many studies documenting the contributory nature of cannabinoids, their receptors, and the skin’s endocannabinoid system in the metabolism of psoriasis and eczema and other inflammatory diseases, of which aging of the skin is considered one.

In the coming years there is great hope for the use of targeted cannabinoid therapies to better control our overall skin health.    

Our topical formulations were developed with the well-being of your skin in mind by enhancing your powerful forces of nature with the highest quality of NANO CBD enhanced formulas soon to be offered in 2019!

Stay tuned, and in the meantime, check out our internal tinctures or One Hit Wonder-ment Skin Oil to get you started here!

All the best, to you and to your skin’s best health. - Kassandra

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References:

M.Pucci, C. Rapino,A. Di Francesco, E. Dainese, C. D’Addario, and M. Maccarone, “Epigenetic Control of Skin Differentiation Genes by Phytocannabinoids,” British Journal of Pharmacology 170, no.3 (2013): 581.doi:10.1111/bph.12309

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4240254/

https://www.naturalproductsinsider.com/beauty/cannabinoids-hemp-beauty-skin-health

CBD and the Endocannabinoid System. Your brain and body are dependent on it.

What is the Endocannabinoid System?

The word endocannabinoid roots itself in Latin, endo meaning within and cannabinoid describing a key in the complex system and is often referred to as the ECS.

The key roles of the ECS are growing daily through research studies by top universities and governing bodies.  

The biological influences of the body’s ECS are many, but to put it simply, it is the neurofeedback system keeping your body in balance despite fluctuations in the external environment.

Keeping your ECS in Balance.

Throughout your body there are cell receptors and corresponding molecules which comprise your endocannabinoid system.

There are two primary cell receptors called Cannabinoid Receptor 1 (CB1) and Cannabinoid Receptor 2 (CB2). Your body produces cannabinoids with the assistance of fatty acids, not unlike those cannabinoids produced in the cannabis plant (hello CBD).

Your endocannabinoid presence acts as the master communicators with your cells to better regulate inflammation, pain, appetite, sleep, mood, insulin sensitivity, fat and energy metabolism, and also impact neurologic and immune conditions.  

Cannabinoids influence the activity of more than 1000 genes, and help increase our cellular antioxidant defenses as well as downregulate many pro-inflammatory mediators.  Most can attest that one of the most appreciated uses of CBD is it’s direct activation of serotonin receptors, providing you an anti-anxiety effect.

The symbiotic relationship of cannabinoids and your ECS.

There are few plants that render the phytochemical abundance of cannabis. Cannabis hosts over 400 unique chemicals and are critical for bioregulation and homeostasis throughout our body and brain.  

What happens when you take CBD internally?

When CBD is ingested, it acts as a supplement, if you will, that kick starts the body’s ECS which is stimulated to produce its own cannabinoids. Current research shows that ingesting CBD actually assists the body in switching on its own capacity for maintaining balance and well-being.  

Read that sentence again so it sinks in: Research is showing that ingesting CBD actually assists the body in switching on its own capacity for maintaining balance and well-being.

Game-Changing Discovery Linking the Brain and the Immune System

Cerebral Health + ECS

Cannabinoids have shown to have a protective effect in the brain and nervous system.  As a powerful neuroprotective antioxidant, CBD is superior to the largely known Vitamin E  and Vitamin C in preventing toxicity from excess amounts of the neurotransmitter glutamate.  

Cannabinoids are now being studied as a target as a new antidepressant and antianxiety solution due to its ability to help to balance mood by their effect on a serotonin receptors.  They even help regulate excitability in the brain, which now shows a track record on the impact on epileptic seizures.

Proactive Neuron Health

Certain cannabinoids offer an overall tonic for the brain, protecting against chronic stress, which can result in a decrease the growth and density of new neurons. They also influence mechanisms that govern the life and death of neurons, suggesting they may be helpful for neurodegenerative conditions and increase the capacity of the brain to adapt, change and remodel itself in response to experience. 

Your Body + ECS

The chronic stress and abundance of toxins in today’s culture is a great burden on our bodies. Cannabinoids are a first line of defence in combating the oxidative stress that burdens us all. They’ve shown to diminish damage related to diabetes, retinal disease, leaky gut, and other conditions associated with oxidative stress and immune activation.

As early adopters of CBD, many start taking Cannabinoids  to address inflammation and pain, which may also support musculoskeletal system function and joint health.  We also know how important recovery from sleep is. Good news! According to a 2017 review of scientific research,  cannabinoids were found helpful in improving disturbances in REM sleep leading to excessive daytime sleepiness.

In summary, nature in her brilliance and infinite creativity, has gifted us with a stream of plant bliss-genes,  blooming perfectly for our own innate regulatory cannabinoid system.

What happens when your ECS does not produce enough cannabinoids or regulate the cells properly?  

We are now starting to discover the everyday and more severe autoimmune health issues to be linked to a  “Endocannabinoid Deficiency Syndrome (ECDS).” I will help you explore this concept in a future article.  

We think CBD taken internally is pretty remarkable, which is why we created our tinctures to keep you in check. I think of our ECS as a great harmonizer, helping us to regain equilibrium and balance.

Thank you for following along and discovering more of your inner-brilliance!

Are you happy?

It’s a journey to INNER JOY….

Everyone you meet always asks if you have a career, are married or own a house; as if life was some kind of grocery list

…. But nobody ever asks if you are happy.

- Heath Ledger

CANNA-PEDIA | Cannabis Terms & Definitions

 

Analgesic

An analgesic is any drug or compound which acts on the peripheral and central nervous systems for the purpose of pain relief. Analgesic drugs are distinct from anesthetics, which have a temporary effect and often completely eliminate sensation or cause unconsciousness. Research into CBD’s effects on humans suggests that it may be an effective analgesic for pain caused by inflammation as well as chronic pain due to illness or injury.

Anandamide

Anandamide (N-arachidonoylethanolamine or AEA) is a neurotransmitter which plays a role in mood regulation. The word originates from the Sanskrit word ananda, which translates to “joy, bliss, delight.” Research has shown that CBD can lead to elevated anandamide levels. CBD is being studied for its therapeutic use in treating anxiety, depression, addiction and other related ailments.

Anorectic

An anorectic is a drug which reduces appetite. Anorectics are also known as anorexics, anorexigens, anorexiants or appetite suppressants. Studies suggest that CBD has anorectic properties and may have potential as a therapy for the treatment of habitual overeating and obesity.

Anti-epileptic

Anti-epileptics (AEDs), also known as anticonvulsants, are the most commonly used drugs for treatment of epilepsy. AEDs are also known to be mood stabilizers and are increasingly being used in the treatment of conditions such as bipolar disorder and borderline personality disorder, as well as for the treatment of neuropathic pain. CBD has been proven in Phase I clinical trials to reduce seizures in patients with intractable epilepsy. Many U.S. states have already approved the use of CBD as an anti-epileptic.

Anti-inflammatory, Inflammation

An anti-inflammatory is a substance which has the ability to reduce inflammation. Inflammation is a natural response of the body to injury or illness. Inflammation often manifests as pain, swelling, redness and heat. Many pain relievers work by reducing inflammation, as opposed to opioids, which block pain signaling to the brain. As shown in numerous studies, one of CBD’s most prominent therapeutic properties is its ability to reduce inflammation.

Anti-insomnia

Anti-insomnia drugs are used to treat sleep disorders. They are intended to induce sleep and prevent premature waking. A variety of studies have shown that CBD may have anti-insomnia properties, and many patients with insomnia claim CBD helps them to fall asleep faster and sleep better.

Anti-ischemic

Anti-ischemic drugs are used to control myocardial ischemia in patients with coronary artery disease. Ischemia is a restriction in blood supply to tissues, which causes a shortage of oxygen required for cellular metabolism. This condition also reduces the availability of nutrients and the removal of metabolic wastes. Research is ongoing as to whether CBD may be an effective anti-ischemic with therapeutic benefits for patients with cardiovascular conditions.

Antipsychotic

Antipsychotic drugs are used to manage psychosis such as delusions, hallucinations, paranoia, schizophrenia and bipolar disorder and are increasingly being used to treat non-psychotic disorders. Pharmaceutical antipsychotics are known to cause unwanted side effects such as involuntary movement disorders, gynecomastia and metabolic syndrome. Research indicates that CBD may have therapeutic properties which may be useful in assisting the treatment of psychosis. Some U.S. states have approved the use of CBD in the treatment of psychosis.

Antispasmodic

Antispasmodic drugs are used to suppresses muscle spasms or to prevent spasms of the stomach, intestine or urinary bladder. Recent research indicates that CBD may have antispasmodic properties and may be useful for the treatment of spastic muscles and for improving digestive motility issues.

Antibacterial

Antibacterial drugs, also known as antibiotics, either kill or inhibit the growth of bacteria and are used in the treatment and prevention of bacterial infections. Some experts consider antibacterials to be external disinfectants such as antibacterial soap, while antibiotics are used as internal medicine. Studies have shown that CBD possesses antibacterial properties.

Antidepressant

Antidepressant drugs are used to treat major depressive disorder, dysthymia, anxiety disorders, obsessive-compulsive disorder, eating disorders, chronic pain, neuropathic pain and, in some cases, dysmenorrhoea (painful menstruation), snoring, migraines, attention-deficit hyperactivity disorder (ADHD/ADD), addiction, dependence and sleep disorders. Many of these ailments are characterized by low levels of anandamide in the brain. CBD has been shown in lab studies to increase levels of anandamide.

Antidiabetic

Antidiabetics are drugs used to treat diabetes by lowering blood sugar levels. Researchers have shown that CBD has the ability to lower blood sugar in animal studies and further research is investigating whether CBD may be useful in treating and preventing diabetes in humans.

Antiemetic

Antiemetic drugs are used to reduce vomiting and nausea caused by conditions such as motion sickness as well as the side effects of opioids and medications used in chemotherapy. Research suggests that oral application of CBD may be an effective antiemetic.

Antifungal

Antifungal compounds, also known as antimycotics, are pharmaceutical fungicides used to treat and prevent fungal conditions such as athlete’s foot, ringworm and candidiasis (thrush), as well as serious systemic infections including cryptococcal meningitis. Studies have shown that CBD possesses antifungal properties and may prove to be useful for these conditions.

Antipsoriatic

Antipsoriatic drugs are used to treat a skin condition known as psoriasis. Numerous studies have attested to CBD’s antipsoriatic properties, suggesting that it may be a useful compound in treating this common skin disorder.

Anxiolytic

Anxiolytic drugs are used to prevent or treat a number of forms of anxiety. Patients suffering from anxiety often have reduced anandamide levels in the brain. CBD has been shown in numerous studies to increase anandamide levels. The treatment of anxiety, including PTSD, is the most common reason given for using CBD. Many U.S. states have approved the use of CBD to treat PTSD and other anxiety-related disorders.

Biphasic

The term biphasic refers to a compound’s propensity to have different effects depending on the dosage being administered. Researchers have shown that, used at lower doses, CBD promotes alertness while at higher doses it promotes sleep.

Cannabidiol (CBD)

Cannabidiol, or CBD, is a phytocannabinoid (a cannabinoid produced in plants), most commonly extracted from industrial hemp, which has been shown to act as a neuromodulating molecule mimicking the effects of certain endocannabinoids(those produced naturally by the human body). CBD has also been shown to have anti-inflammatory, antioxidant and antibacterial properties, among others.

Cannabinoid

Cannabinoids are a class of molecules which have neuromodulating effects in the human body. Endocannabinoids are those produced by the human body, whereas phytocannabinoids are those produced by plants such as cannabis. CBD is a phytocannabinoid compound.

Cannabis

Cannabis is a species of plant which produces phytocannabinoids, such as CBD, which is known to have medicinally therapeutic benefits. Phytocannabinoids have been shown to mimic the effects of signaling molecules known as endocannabinoids, which are naturally produced by the human body. Hemp and marijuana are both varieties of cannabis.

Cannabinoid Receptor

Cannabinoid receptors are of a class of cell membrane receptors which interact with both endocannabinoids (human cannabinoids) and phytocannabinoids (plant-derived cannabinoids). There are two types of cannabinoid receptors in the human endocannabinoid system — CB1 and CB2. CB1 receptors are found mainly in the brain and central nervous system, and CB2 are found throughout the body, especially in the cells or other major organs. The endocannabinoid system is involved in a variety of physiological processes including modulation of appetite, pain-sensation, mood and memory.

CBD Oil

CBD oil refers to either the essential oil extracted from CBD-rich cannabis varieties such as hemp, or medicinal oils which have been infused with CBD. CBD oil is commonly used for its supplemental and medicinal benefits.

CBDa

CBDa is the acid form of cannabidiol. When heated to a certain temperature for a certain amount of time, CBDa is converted into CBD. The process of converting CBDa into CBD is known as decarboxylation.

CBD-Rich

This term refers to the essential extract of a hemp plant which is high in CBD.

CBD Enriched

This term refers to a product which has been enriched by infusing it with CBD.

Cannabidivarin (CBDv)

Cannabidivarin, or CBDv, is a non-psychotropic cannabinoid found in Cannabis. CBDv is thought to have therapeutic properties similar to those of CBD such as reducing nausea.

CBD Concentrate, CBD Distillate

CBD concentrate or CBD distillate refers to a distilled reduction of raw hemp extract. A distillation process is used to remove waxes and other compounds to produce a product with a higher-than-natural concentration of CBD.

CBD Isolate

CBD Isolate is a crystalline form of pure CBD which is made by subjecting hemp extract to a series of distillation processes which remove all other compounds leaving behind only pure CBD. CBD isolate is often used in CBD-enrichedpreparations such as vape oil.

Decarboxylation

Decarboxylation refers to a process by which a carbon atom is removed from a carbon chain in CBDa, converting it to CBD, which is more easily absorbed and metabolized by the human body. This is usually done by exposing the compound to higher temperatures for a period of time.

Edibles

This term refers to edible preparations that have been infused with CBD, such as candies and baked goods. CBD-infused edibles are often used to treat ailments of the stomach and intestines.

Endocannabinoid

An endocannabinoid is a cannabinoid compound produced naturally by the human body. Endocannabinoids are part of the human endocannabinoid system, or ECS.

Endocannabinoid System (ECS)

The human endocannabinoid system, or ECS, consists of cannabinoid compounds produced by the human body and their associated cannabinoid receptors. The ECS acts as a signaling system which has the ability to modulate a number of physiological processes on a cellular level.

Entourage Effect

This term refers to the combined overall therapeutic effects produced by the active compounds found in CBD-rich hemp extracts such as cannabinoids and terpenes, each of which has its own particular set of effects.

Essential Oil

Essential oil refers to an oil which has been extracted from a plant. In the case of hemp, this essential oil contains a host of cannabinoids and terpenes as well as other compounds such as chlorophyll. Some extraction processes remove compounds such as chlorophyll while leaving the cannabinoids and terpenes intact.

Extract, Extraction

An extract is the end product of an essential oil extraction process. In the case of hemp, the essential oils are extracted using a solvent such as supercritical CO2 or ethanol. The resulting product is referred to as hemp extract.

Full Spectrum

A full spectrum CBD oil is a product which contains a variety of cannabinoids and terpenes. Full spectrum oils are valued for their part in the entourage effect.

Gel Capsule, Gelcap

A gel capsule, also known as a gelcap, is a capsule made from gelatin and other ingredients which contains a medicine or supplement —  in this case, CBD oil — to be administered orally.

Hemp Oil / Hemp Seed Oil

Hemp seed oil, also sometimes referred to as simply hemp oil, is the oil produced by pressing hemp seeds. It is not to be confused with the plant’s essential oils,which are extracted from the plant’s flowers and leaves. Hemp seed oil contains neither cannabinoids nor terpenes; however, it is rich in vitamins, minerals, amino acids and essential fatty acids, and is often used as a base for producing CBD oil.

Hemp, Agricultural Hemp, Industrial Hemp

Hemp is a variety of cannabis which is used for agricultural and industrial purposes such as textiles, construction materials, biofuels and food. Unlike marijuana, another variety of cannabis, hemp contains negligible amounts of the psychotropic cannabinoid, THC.

Homeostasis

This term refers to a state of human physiology in which a variety of physiological processes are well balanced, producing a state of good health. CBD is often used to maintain or promote a state of homeostasis.

Immunomodulator

An immunomodulator is a chemical agent which is used to modify human immune response or improve the functioning of the immune system. Research suggests that CBD possesses immunomodulation properties.

Inhaler

An inhaler is a medical device which is used to administer a measured dose of a medicinal compound such as CBD via the lungs. Inhalers are used primarily to treat asthma and other forms of lung inflammation.

Intestinal Prokinetic

Intestinal prokinetics are drugs used to treat intestinal motility disorders. Some researchers believe that these conditions may be the result of an endocannabinoiddeficiency and that CBD may be useful in treating them.

Marijuana

Marijuana is a variety of cannabis which contains high levels of THC, a psychotropiccannabinoid. Marijuana is not to be confused with hemp, which has negligible amounts of THC.

MCT Oil

This term refers to medium-chain triglycerides, a form of saturated fatty acids. Commonly made from coconut oil, MCTs provide a variety of health benefits including improved cognitive function and weight management. MCT oil is often used as an ingredient or base for CBD-enriched oils.

Metabolism

This term refers to the life-sustaining chemical processes which occur within cells, such as the conversion of sugars and fats to energy and the elimination of wastes. It can also refer to the combined chemical reactions which sustain living organisms. The endocannabinoid system is thought to be involved in the regulation of some of these processes.

Metabolite

A metabolite is the waste product of a compound which has been through the process of metabolism.

Nanoencapsulation, Microencapsulation

Nanoencapsulation and microencapsulation are processes by which CBD oil is converted into a water-soluble preparation by encapsulating the oil in microscopic beads of an emulsifier or wax, allowing them to be more readily absorbed into the bloodstream.

Neuroprotectant

This term refers to a compound’s ability to protect or repair neurons and other nerves in the central nervous system from various types of damage. CBD has been shown in multiple lab studies to have neuroprotective properties.

Neuropathic Pain

Neuropathic pain refers to a type of chronic pain which results from damage to the central nervous system, caused by conditions such as diabetes. Research studies have shown that CBD may be a useful therapeutic agent in the treatment of neuropathic pain and many U.S. states have approved the use of CBD as a treatment for neuropathic pain.

Neurotransmitter

A neurotransmitter is a chemical substance released from the synapses where nerves connect to other nerves, muscles or other structures, triggering an impulse. Research has shown that CBD may be an effective modulator of neurotransmitters such as anandamide.

Phytocannabinoid

Phytocannabinoids are cannabinoids produced by plants such as hemp. CBD is a phytocannabinoid which has the ability to mimic cannabinoids produced naturally by the human body, which we call endocannabinoids.

Psychoactive, Non-Psychoactive

A psychoactive drug or chemical is one that changes brain function and results in alterations in mood or behavior such as relieving anxiety. CBD is psychoactive in that it can alter mood and may reduce anxiety. Many U.S. states have approved the use of CBD to treat anxiety-related conditions such as PTSD.

Psychotoxic, Non-psychotoxic

A psychotoxic drug or chemical is one that produces detrimental effects on brain function such as causing psychosis, depression, anxiety or hallucinations. CBD is non-psychotoxic.

Psychotropic, Non-psychotropic

A psychotropic drug or chemical is one that alters brain function in such a way as to cause changes in cognition and behavior like causing a high or euphoric feeling. THC is psychotropic. CBD is non-psychotropic.

Sublingual

A sublingual medication or supplement is one that is administered under the tongue and absorbed into the bloodstream via capillaries in the tissues on the inside of the mouth. A liquid sublingual such as CBD oil is often referred to as a tincture.

Terpenes, Terpenoids

Terpenes are oily compounds produced by plants such as cannabis which give it it’s aromas and flavors. Many terpenes are physiologically active when consumed. For example, a terpene called limonene is responsible for the smell of citrus fruits and can have an uplifting effect on mood. A terpenoid is a metabolite of a terpene.

THC: Δ9-tetrahydrocannabinol

THC is the psychotropic cannabinoid produced in marijuana which causes a feeling of euphoria. Hemp, hemp extract and CBD oil made from hemp extract do not generally contain THC.

Tincture

A tincture is a liquid preparation such as CBD oil which can be administered sublingually.

Topical

A topical is a liquid, cream or balm that is applied externally to the skin and absorbed into the body. CBD infused topicals are used to treat skin conditions as well as to reduce inflammation and relax tense muscles.

Toxic, Non-toxic

A toxic substance is one that is poisonous or harmful to human tissue and organs.CBD is non-toxic.

Transdermal

A transdermal preparation is one that is applied to the skin via a patch. The active ingredient is then absorbed into the bloodstream via the skin. CBD can be administered in the form of a transdermal patch.

Vaporizer, Vape, Vaping

A vaporizer, or vape, is an implement which atomizes or gasifies a solid or liquid substance so that it may be inhaled and absorbed into the bloodstream via the lungs. Oils used in vaporizers are often referred to as vape oil. Vaping is the act of using a vaporizer. Vape oils can be infused with full spectrum CBD oil or CBD isolate.

Vasorelaxant

A vasorelaxant is any drug or compound used for its ability to relax arteries, veins and capillaries for the purpose of lowering blood pressure. CBD has been shown in numerous studies to exhibit vasorelaxant properties.

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SHOP CBD HERE!  Natural - Organic - 100% THC Free

SHOP CBD HERE!  Natural - Organic - 100% THC Free

Anxiety & Depression. Using CBD for a Happy Go Lucky Life!

Hi!   Get a little anxiety from time to time?  Who doesn't! Living with it daily, is a problem.

I'm staying outside the spiritual and mindfulness  self assessment path on this post - and strictly focusing on the healing benefits of the medicinal plant world that we rely on and share a rich existence with.  

General Anxiety an depression is at all ages and ranges, and has put mental health awareness on the rise.  

Life events, work stressors to menopause hormonal shifts easily effects our brains activity level - in which holds us back from living life at it's best. 

I recently ran across some stressful U.S. statistics:

• 48% of people say stress and anxiety has a negative effect on their life and work.
• 78% experience physical symptoms caused by stress and 73% experience psychological symptoms.
• 48% say stress has increased for them in the last 5 years.

if you’re one of those people, cannabinoid medicine
might be able to help you.

Image: Doen

What Is CBD, and How Does It Work?

CBD, or cannabidiol, is a chemical compound found exclusively in the cannabis plant. Unlike THC, CBD does not cause a high. Because of its increasing evidence of its numerous health benefits. One benefit seen from many of our CBD users, is the experience of less anxiety.

Getting Happy - Go - Lucky.     
How tho?  

Experts believe that it reduces anxiety by influencing what’s going on in your brain. Your brain is an astoundingly complex system that controls every interaction in your body.  Every thought and feeling you have is the result of its billions of nerve cells and chemicals, which are constantly interacting together.

Usually, all these chemical reactions go smoothly and you feel happy and healthy, but sometimes the chemicals cause feelings that you don’t want, like anxiety. Experts believe that when this happens, CBD can be used to change the chemistry in your brain and throughout your body, and get things running smoothly again.

Those who had taken cbd experienced significantly less anxiety and discomfort than those who received the placebo.

Evidence: The anecdotal evidence on CBD is abundant, which has brought many men and women to a fork in the road of choosing CBD a try for their anxiety

Receptor Systems in the Brain

>> The brain contains large numbers of highly specialized cells called neurons.

>> Each neuron connects to many others through structures called synapses.

>> These are sites where one neuron communicates to another by releasing chemical messengers known as neurotransmitters.

A neuron’s sensitivity to a specific neurotransmitter depends on whether or not it contains a receptor that “fits” that transmitter.  If a neuron contains receptors that match a particular neurotransmitter, then it can respond directly to that transmitter. All neurons contain multiple neurotransmitter receptors, allowing them to respond to some neurotransmitters but not others.

Plant Medicine & Receptors

Brain receptors are not only sensitive to neurotransmitters produced naturally within the brain, like dopamine or serotonin, but also chemical messengers produced outside the body, such as plant cannabinoids like THC or CBD.

So when you ingest an edible or tonic, the components travel through your bloodstream, and enter your brain. Once they arrive, these plant-derived compounds influence brain activity by interacting with receptors on neurons. But they don’t interact with all neurons, just the ones that have the appropriate receptors.

CBD and the Receptor Systems [and the misconceptions]

Although it is a cannabinoid, CBD does not directly interact with the two classical cannabinoid receptors (CB1 and CB2).  Instead, it affects signaling through CB1 and CB2 receptors indirectly. This partly explains why, in contrast to THC, CBD is non-intoxicating. In addition to its indirect influence on the CB1 and CB2 receptors, CBD can increase levels of the body’s own naturally-produced cannabinoids (known as endocannabinoids) by inhibiting the enzymes that break them down.

Even more intriguing: CBD also influences many non-cannabinoid receptor systems in the brain, interacting with receptors sensitive to a variety of drugs and neurotransmitters.  

CBD & Opioids

These include opioid receptors, known for their role in pain regulation. Opioid receptors are the key targets of pharmaceutical pain killers and drugs of abuse such as morphine, heroin, and fentanyl.

CBD can also interact with dopamine receptors, which play a crucial role in regulating many aspects of behavior and cognition, including motivation and reward-seeking behavior.

This raises the intriguing possibility that CBD’s ability to influence either opioid or dopamine receptors may underlie its ability to dampen drug cravings and withdrawal symptoms, effects directly relevant to the treatment of addiction.

CBD and a Happy Serotonin System

CBD’s ability to target a specific serotonin receptor, the serotonin 1A receptor, is associated with a remarkable range of therapeutic possibilities.

Professor Roger Pertwee, a pharmacologist from the University of Aberdeen, spoke with Leafly about this aspect of CBD biology.

“It’s apparent ability to enhance the activation of serotonin 1A receptors supports the possibility that it could be used to ameliorate disorders that include: opioid dependence, neuropathic pain, depression and anxiety disorders, nausea and vomiting (e.g. from chemotherapy), and negative symptoms of schizophrenia,” he said. “One big unanswered question is what the human clinical relevance and importance of each of these potential therapeutic uses of CBD, identified solely by examining data from non-human preclinical research, actually is.”

CBD Partnering with Complex Pharmacology

Understanding CBD’s neurological effects is a complicated business, because of the wide variety of receptors with which it interacts.  But that complexity may be the key to its promise as a therapeutic agent.

Motivational disorders like addiction and anxiety are themselves highly complex; they arise from incompletely understood causes that span multiple receptor systems and neural networks in the brain. CBD’s complex, multi-target effects may therefore be crucial to its potential for aiding the treatment of such disorders. Over the coming years, researchers will continue to further understand this complexity and uncover the full scope of CBD’s therapeutic potential.

So How Do I Use It?

Unfortunately, since CBD hasn’t been officially approved by the U.S. Food and Drug Administration as a treatment for anxiety, there are no official guidelines on how to use it if you decide to do so. Most experts recommend starting with a low dose, and working your way up slowly, taking note of how it makes you feel. Everybody reacts differently to CBD

Studies state 300-600mg per day brings relief.  

A lot of people do seem to be finding their own sweet spot. In a 2017 survey of 2,400 people from the medicinal cannabis community, researchers found that the majority use CBD products, and the most common medical condition they are using it for is anxiety.

Most of the CBD-users in this study reported that CBD works very well, with 42 percent saying that they have actually stopped using traditional medications now that they use CBD. Great news!

As noted, research validates that starting with 300-600mg can benefit the user. From my experience, this is good starting place to begin building on your specific needs.  Most likely, the body's not just experiencing "anxiety." Theres a root origin that intertwines a myriad of physiological and mental symptoms together.  So in conclusion, as an adaptogen like compound, the receptors feed what is most deficient first.  

Find our Advanced Terpene Rich + Broad Spectrum 300MG CBD HERE. 

A little more tense?  Our 1000mg CBD + CBG is a HOT SELLER for instant and long lasting benefits.  This tonic is also infused with additional terpenes and an additional cannabinoid profile for incredible healing power and bioavailability. Find that HERE.

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.What About the Risks?

The good news is that despite the lack of FDA approval, people commonly take CBD for anxiety and a wide range of other health and wellness benefits, and negative side effects don’t seem to be too common.

Many people prefer CBD—clinically tested or not—to other common anti-anxiety drugs since these other options can cause some fairly unpleasant side effects; things like confusion, muscle weakness, and vomiting. Anti-anxiety medications can also be very addictive. In one 2017 review researchers conclude that the potential side effects of CBD are generally much more tolerable than those from alternative medications.

Here are eight lifestyle antidotes to be aware of when addressing anxiety and stress:

Keep your relationships strong. You may have 1,000 Facebook Friends and 500 LinkedIn connections, but do you have at least a few close relationships with people who care about you and whom you trust? These are people where you have regular interactions in more than 140 character sound-bites: where you speak about what’s really going on with you and find support and encouragement.

Resolve conflicts quickly. Do you have unresolved relationship tension that’s causing stress? Are you holding a grudge? Maybe it’s time to deal with these and move on. Trying to avoid relationship challenges is usually more draining long-term than having that difficult but needed conversation now.

Don’t worry. Worrying is stressful. It saps energy, life, creativity and resilience. We all worry; the key is not getting stuck there. There are several ways out:

Ask for help. One way out of worry may involve asking a boss, mentor or co-worker for advice or for a hand in getting something done. Or maybe you find yourself taking too long to complete a task because you’re over-analyzing it. If so, collaborate with a “doer” to help you get to decision and action. Delegate. Pray. Or all of the above.

Be thankful. It is amazing how remembering to be grateful can positively shift perspective and reduce worry and stress. How might you develop and maintain an attitude of gratitude?

Stay positive. With bad news, difficult circumstances, Debbie Downers and Doug and Wendy Whiners all around us, focusing intentionally on the good can be like swimming upstream. Get time with positive people. And mix inspirational reading and reflection into your day so your thought life and attitude isn’t governed purely by your intake of news and entertainment.

Do what’s important. Some of us are addicted to busyness; and it’s easy to get busy with stuff that’s not really important. Clarifying what is important and where we really want to say “yes” makes it easier to say “no” to distractions that just wind up creating more stress.

Take care of yourself. Find an exercise routine that works for you. Eat well. Get the rest you need. These habits make a huge difference when it comes to increasing your energy and preventing and coping with stress.

Resource: https://www.leafly.com/news/science-tech/what-does-cbd-do

CBD and Breast Cancer [and what research says]

There’s a lot of research out there and it can be overwhelming!   I'm devoted to providing validated research that crystalizes clarity for you to get the information you need to help you and your family live healthier lives.

As you read through, I encourage you to frame this information with gratitude of the present knowledge we have available and the options from both the natural realms - and western medicine opportunities at hand when it comes to addressing cancer.   There is certainly no cure all - but as self advocates, knowledge is king ( ok...queen)!

CBD & Breast Cancer

Besides skin cancer, breast cancer is the most common cancer among women in the United States. The great news is that many researchers have found evidence that CBD may be able to slow the progression of invasive breast cancer, which will affect approximately 1 in 8 U.S. women at some point in their lives.

CBD is a non-psychoactive cannabinoid found in the stalks, seeds, and flowers of cannabis plants like hemp. 

After breast cancer is identified and diagnosed, the efforts move towards inhibiting the  spread of the cancerous tumor. When reaching beyond the breast and nearby lymph nodes, it’s considered advanced, or metastatic.  

The great news is that studies over the recent years suggest that CBD may help inhibit metastasis in breast cancer cells. In 2014, researchers from the California Pacific Medical Research Center found that CBD appears to inhibit the Id-1 and Akt genes, which have been known to play a role in tumor growth.  Study: CBD Kills Breast Cancer Cells 

Here’s an excerpt from this study conducted by the  American Association for Cancer Research 

“It suggests that cannabinoid-based medicines may be useful for the treatment of most breast tumor subtypes, stating that “these compounds exert anti-proliferative, pro-apoptotic [cell-killing], anti-migratory and anti-invasive actions in a wide spectrum of cancer cells in culture.” 

With a 1 in 8 stat, we all know a family who has been affected by breast cancer.   My hope is that whether we have a chronic or threatening disease, we shift to preventative care by using CBD as part of our self-care routines on a daily basis. 

The United States government has been resistant to recognizing the therapeutic properties of cannabinoids, but has now recently declared in agreement that it has medicinal benefits by creating a pharmaceutical synthetic form of CBD.  Cannabinoids vs. Cancer  

From the TOP - DOWN.
The National Cancer Institute (NCI), under the U.S. Department of Health and Human Services, updated its website to acknowledge the benefits of cannabinoids as a “treatment for people with cancer-related symptoms caused by the disease itself or its treatment.”

In short, the NCI describes CBD as potentially benefiting those with breast cancer in two separate capacities:

• CBD has demonstrated anti-cancer properties
• CBD can help patients manage symptoms related to cancer treatments

In Depth: The Findings of CBD’s Anti-Breast Cancer Properties

In its overview on cannabinoid research, the NCI highlights the findings of studies suggesting CBD is potentially beneficial for fighting and inhibiting the spread of breast cancer.

These anti-cancer effects may be related to CBD’s influence over the endocannabinoid system’s CB1 and CB2receptors, as one study confirmed that CB1 and CB2 receptors are potential targets in breast cancer. However, an in vitro study looking at the effect of CBD on breast cancer found that the compound effectively “induced programmed cell death, independent of the CB1, CB2, or vanilloid receptors.”

In that in vivo study, CBD was able to inhibit the survival of breast cancer cells by inducing apoptosis, a process of programmed cell death. The higher concentration of CBD administered, the greater the anti-breast cancer effects were. At the same time, CBD had little effect on normal breast cells.

The NCI points out that other preclinical studies have found evidence of CBD’s anti-tumor effects in breast cancer. CBD has also shown to increase the uptake of traditional anti-cancer drugs to improve their efficacy for inducing apoptosis of cancer cells, according to the findings.

 “The potential benefits of medicinal [cannabinoids] for people living with cancer include antiemetic effects, appetite stimulation, pain relief, and improved sleep,” according to the NCI page.

Studies have found CBD to reduce nausea and vomiting caused by common cancer treatments like chemotherapy. In several animal models, the compound has also shown to have anxiolytic properties to reduce anxiety and regulate mood.

“CBD, in particular, is thought to have significant analgesic, anti-inflammatory, and anxiolytic activity without the psychoactive effect (high) of delta-9-THC,” reads the NCI page.

Other Groundbreaking Findings About Cannabinoids

The benefits from daily use of CBD are without bounds.  Attitudes toward cannabis are shifting as credible medical research efforts continue to reveal the plant’s exciting therapeutic potential.

Ample studies over the past decade, medical research has made intriguing discoveries about cannabis and its therapeutic effects. Studies have shown that medical cannabis:

• can slow the progression of Alzheimer’s and Parkinson’s diseases
• reduces the debilitating seizures caused by epilepsy 
• reduces spasms experienced by those with multiple sclerosis 
• minimizes the neurological damage caused by spinal cord and traumatic brain injuries
• can boost bone density and assist in healing.

 OVERCOME FEAR WITH KNOWLEDGE

In conclusion, OVERCOME FEAR WITH KNOWLEDGE and share with friends and family.  Remain updated on the available resources to help you make an informed decision.

We've listened to the many questions people have raised, and have worked diligently to supply a comprehensive cannabinoid education and purchasable phyto-cannabinoids natural and organic medicinal tincture options for you to explore and experience.

Learn how cannabinoids naturally interacts with the body’s systems, and become clear on the quality versus confusion of the array of products available. If you decide cannabinoids are right for you, feel free to reach out with any questions you may have - I'm happy to help!  

This loving plant is here to stay, and while its not the "cure all," it's synergistic value it brings to the formulated components that surround it, bring extreme bioavailability and benefits to those that believe in it.  

All my love -  Kassandra 

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