How CBD Interacts With Medicines


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In a previous editorial, I address this topic more in depth, but to get the quick and easy explanation, it’s all rolled out here.

Let’s dig in!

Cannabidiol (CBD) itself has no dangerous interactions with other drugs you may be taking.

But there is one exception:
Full Spectrum CBD might indirectly affect other pharmaceuticals by increasing their strength. This is because CBD stops a certain particle in your body from working effectively.
The liver enzyme Cytochrome P450 is essential for your body. It metabolizes almost all the drugs we consumed. It breaks down the substances you put in your body, and turns them into simpler substances that your body actually knows how to use.
Because of how complicated most medicines are, this means Cytochrome P450 alone allows us to break down over 60% of prescribed medicines.


Sounds important right?

Now this is the issue:
If you take a large dose of CBD, your body’s P450 enzymes will be temporarily inactive.
When those enzymes are inactive, it becomes much harder for your body to process almost every drug out there.

This means:

Taking lots of CBD will greatly increase the effects of any prescriptions drugs on your body.
As they cannot be processed, the drugs will just stay in your body instead of being digested as they should.


What does this mean?
This is both good and bad:

  • The good side is that there may be a possibility to reduce the amount of powerful prescription medications you take (speak to your physician before beginning or stopping medication). Regardless of what you take, it’s always best to put less artificial drugs into your body.

  • The bad side is just that you need to be careful. If you are taking CBD make sure to talk to a medical professional and reduce the amount of prescription drugs you are taking.

Again:

Cannabidiol (CBD) itself has no dangerous interactions with other drugs you may be taking according to medical journals. (more information can be found projectcbd.org).

Here's a list of possible drug interactions on https://www.drugs.com/drug-interactions/cannabis.html


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