Beauty Biology

How Cellular Health Directly Effects Aging & Skin Health [tips inside]

In my previous article, I noted that our body’s biological system is influenced by our genetics. In fact - science proves that 80% of our health state is from the daily choices and our direct environment. The other 20% is hard coded. This should come a a great relief (and a little pressure of course).

Why our skin ages and what we can do about it.

Aging occurs because of two different factors: intrinsic and extrinsic. You don't have much control over intrinsic factors, which are influenced by your genes, ethnicity, and certain medical conditions. But there is a major upside because you can have a huge impact on your extrinsic factors like UV exposure, stress, smoking, nutrition and lifestyle choices, which are major contributors to the aging process.

How do these extrinsic factors contribute to aging? All of them can generate the trifecta of reactions that create fines lines, wrinkles, and skin sag: oxidation, inflammation, and glycation. When you combine these three things, you hit the jackpot for premature aging.

Below we get one to one on terminology, how it effects our fundamental biology, and how to integrate lifestyle and nutritional habits to assist healthy aging and brighter skin.

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Oxidation

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Mitochondria are tiny "organelles," thousands of them in each cell, that are the power plants for our metabolisms. Their waste products include oxygen in a form that is super-reactive and therefore toxic. The cell has an effective mechanism for quenching these ROS (reactive oxygen species).


Insulin chemistry

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The body gradually loses its ability to respond to insulin, and poisons itself with excess blood sugar.

All the food you eat gets converted into glucose, which is the simplest form of sugar that your body can use for energy. Foods containing more sugar—think packaged cereal, crackers, sauces as well as foods that are more readily converted into sugar like refined carbohydrates—can flood your system with glucose.


Glycation (cross-linking of proteins and sugars)

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Skin + Glycation

When sugar combines with protein or fat in the bloodstream, the result is the formation of harmful compounds called advanced glycation end products (also knowns as AGEs). AGEs can be formed spontaneously in the body or they can be formed in foods like fried foods and highly processed products like red meat, margarine, nuts, and butter. Cooking methods using high temperatures—like frying, grilling, and toasting—can also contribute to AGEs formation.

In your skin, AGEs are formed with collagen and elastin causing these fibers, which are integral to a supple and youthful appearance, to become stiff, inflexible, and prone to breakage. Translation: Your skin becomes less elastic, wrinkled, saggy, and more vulnerable to sun damage.


Inflammation

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An important tool for fighting infection, but it becomes over-reactive in old age, and the body begins attacking itself. Excessive inflammation plays a central role in cardio disease and in arthritis, and a lesser role in Alzheimer's disease

Skin +Inflammation: Your body is on a roller coaster of high and low blood sugar spikes and labile insulin levels, which can lead to skin sag, inflammation, and chronic disease. Chronic inflammation is at the root of chronic disease systemwide and your skin is no exception. Inflammation can worsen rosacea, psoriasis, and eczema and can also weaken the collagen and elastin in your skin over time, leading to skin laxity, poor wound healing, and uneven tone and texture.


Apoptosis

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A term for programmed cell suicide. Cells are programmed to die when they are unhealthy or when they become cancerous.

But there is evidence that in old age, healthy cells undergo apoptosis as part of the body's self-destruction program.



Telomeres & Replicative Senescence

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All cells have built-in counters called telomeres tacked on to the end of each chromosome. With each time the cell reproduces, the telomere becomes shorter, and eventually the cell to stop reproducing.

Longer telomeres have longer life spans.


De-methylation

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With age, DNA loses methyl groups that control gene expression, and as a result genes are expressed in the wrong place at the wrong time.





Let’s recap with some final tips!

Addressing Cellular Health by Eating for a Youthful Glow ….

So in closing, there are a lot of things in our food supply and environment that threaten our skin health, cellular health and our overall mood and appearance. Focusing on certain foods can make a huge ( all the ) difference.

1. Antioxidant-rich foods

Eating foods rich in antioxidants like tomatoes (lycopene), berries (polyphenols), dark leafy greens (Vitamin E), and spinach (carotenoids) can limit damage caused by free radicals and AGEs. Pair your meal with a few cups of green tea (catechins) and coffee (caffeic acid) for an added boost.

2. Anti-inflammatory foods

Adding in foods rich in carotenoid plant compounds like lycopene (tomatoes, watermelon, and guava), lutein (pumpkin, pistachio, dark leafy greens), and zeaxanthin (parsley, kale, egg yolk) will give you an anti-inflammatory and antioxidant jolt. Foods rich in zinc, selenium, and copper like lentils, eggs, dark chocolate and almonds are also vital to the formation of collagen and elastin and help decrease inflammation.

3. Anti-glycation foods

Foods that limit rapid, sharp spikes in blood sugar can help limit AGE formation. So can utilizing cooking methods using low temperatures and water-based moisture like steaming, poaching, and stewing.

Apples, asparagus, figs, celery, green peppers, cauliflower, and onions have been shown to combat the process of glycation as they are rich in phytonutrients, beneficial compounds, including rutin, quercetin, and luteolin.

Adding in high fiber vegetables like artichokes and broccoli, as well as herbs and spices including cinnamon, ginger, turmeric, garlic, sage, thyme, and fenugreek can help keep blood sugar levels steady and block collagen-damaging AGEs.

The best part of all of this is that these foods can be used in so many delicious recipes. Protecting your skin doesn't mean only eating bland, boring food. So bon appetit and cheers to long-term skin health.

Hippocrates is famously quoted for saying, "Let food be thy medicine, and medicine be thy food," but I would argue that food can be the fountain of youth, too.

Love n Light - Kassandra

The 5 Key Triggers of Female Hair Loss (and a natural solution 2x's more powerful than minoxidil)

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Hey lovely!
I wanted to speak with you about a topic and experience many women go through. Even though it's a vanity, it runs emotionally deep.

Been here?
Whether post-baby, post trauma, post-menopause, when your hair becomes noticeably thinner, we freak out and grow (no pun intended) self-conscious and anxious if it will stop.

I've been there. Last year I uncovered I was severely anemic, in which became a catalyst of over 50% hair loss. I remember pulling out handfuls, driving me into deep despair.

I QUICKLY HAD A DIRECT AFFINITY AS A HAIR LOSS SPECIALIST, AND NOW HAVING MASSIVE LOSS, MYSELF.

Given the right tools, I've successfully regained the loss hair, and I truly believe that with the right information - we can slow loss - and potentially grow back what's been rinsed down the drain with the right testing tools, expertise and safe products.

I know ONE THING. Dissolving the triggers and getting to the ROOT, is the best way to make it stop.

Because if left untreated, over time, thinning can worsen significantly.

Get to the ROOT and invest in understanding why it is happening in the first place.

Take a closer look at the five common reasons women experience hair loss.


#1: HORMONAL IMBALANCES

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Many of the most common causes of hair loss in women center around hormone changes. When the hormones change – either too much or too little occurs – this changes the way the body works. In most people, even slight changes can create shifts in the way the body operates. Hormones can cause hair loss to occur for various reasons. Most commonly, it occurs because the body pulls away hair production to focus on other tasks in the body, such as inflammation. Hormone imbalances can be a good thing, though. Most of the time, they can be improved upon, allowing hair to regrow once your hormone levels are more in balance.


#2: POOR DIET

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If your diet is not what it should be, it will show in your hair. It is very common for individuals who have a poor diet to struggle with hair loss. Imagine the cells in your follicles needing nutrition. When they do not get the nutrition necessary, this commonly leads to the cells being unable to work properly. When this happens, your body cannot produce the hair you normally have. A key culprit of this is iron deficiency. Iron is critical for the development of healthy and beautiful hair, yet many women do not get enough of it in their diet.


#3: STRESS

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There is no bigger trigger to significant hair loss in a sudden manner than stress. Stress is a form of hormone imbalance. When the body is faced with a stressful situation, it must react. To do so, it must determine where to send nutrients and oxygen. It tends to send this to the cells that need to react fastest. Hair tends to fall out because of a lack of nutrients as a result. It is very common for stressful situations – such as changes in lifestyle or diet or traumatic events – to lead to some level of hair loss. This tends to be very sudden and unexpected.


#4: MEDICATION

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Some medications can cause hair loss to occur. It is very common in women (as well as men) who are undergoing chemotherapy. Some forms of chemotherapy target the actively growing cells in the body. Since your hair is continuously growing, chemo tends to lead to hair loss. Other medications can do this as well. If you just started a new medication and you are facing this type of symptom, it is time to speak to your doctor about it. Most often, once you stop taking that medication – if your doctor approves – you may see your hair growth return.


#5: PREGNANCY

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The body changes massively during pregnancy. Hair loss tends to be one of the victims of the process. When pregnancy occurs, the body must adjust hormone levels to compensate. As a result of this, the pregnancy can cause women to lose some of their hair, especially two to 4 months after the baby is born. Once your hormones levels are back to normal, hair growth will normalize as well.


IN CLOSING, LET’S GET A PLAN.

Why is your hair loss happening? You’re incredibly unique, and it cannot be said for sure until you visit a functional medicine practitioner or doctor to inquire about your options and your needs. Make sure you check all hormones, including TPO, Thyroid, T3/T4 conversion, iron and nutritional value. Whoofta!

Most importantly, it is essential that you address your concerns right away. Hair loss, especially sudden hair loss, can be cause for underlying health concerns.

What about scalp topicals? I firmly believe in a multi-purposeful approach. If you’d like to learn how I’ve helped hundreds of women jump start their HAIR GROWTH, then check out our Root Revival Hair Loss Kit and Tonic HERE!

Get on the Evoq Re-growth Plan

It’s a powerful and proven to be 2x's more powerful than minoxidil!

Natural?

YES - completely chemical free, leaving no grease or weight on the scalp.

Add These Most Influential Foods for Genetic Health and Aging



Hi there!

Genetics, 23 and Me, and MTHR are all phrases you’ve possibly seen in the last year around the discussion of optimizing our genetic health.

I’m also sure you’ve heard of the “80/20” rule. Well, below you’ll learn the importance and how I’ve put a new flare to this concept and relate it to our DNA health.

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How?

The truth of the matter is that in relation to genetics - science proves that 80% of our health state is from the daily choices and our direct environment. The other 20% is hard coded. This should come a a great relief (and a little pressure of course).

Did you know our nutrition has a DNA to it as well? It’s how it helps heals us.

Improve Your Longevity and Aging Adding Epigenetic Influence of Foods and Supplements

Learning more about what we eat and what impact it may have on our bodies, especially the potential epigenetic impact it may have on our DNA – the very “code of life” – is just one step on the path to better health.

When’s the last time you really thought about how the foods you eat positively or negatively affect your body, health, and wellbeing?

With more research and an increasing amount of practitioners, we can begin to unravel the mysteries of what may be contributing to our ailments and what could be done to help improve our health with a much more comprehensive understanding.

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It’s intriguing to follow the progress of epigenetic testing and the benefits that analyzing the epigenome can have on guiding proper health regimens.

Polyphenols, for example, which are found in foods such as fruits, vegetables, olives, and chocolate, have been shown to be effective in promoting resilience again stress and reducing depression.

The combination of these compounds were found to epigenetically reduce stress and depression by modulating inflammatory responses and synaptic plasticity in the brains of those with depression.


Cool right?

So just for you, here’s the list of the most powerful foods studied to address your genetic health at the cellular level?

To age better. Feel better. To think better.



The Most Influential Foods for Genetic Health and Aging

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Broccoli sprouts—Best source of sulforaphane, which prevents brain aging, excess estrogen and lowers cancer risk.

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Pomegranate—anti-oxidant which appears also to reduce blood cholesterol count.



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Blueberries.

Neuroprotection, hearing and memory loss, possible anti-cancer benefits.

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Ginger.

anti-inflammatory action via several independent mechanisms


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Curcumin.

Anti-inflammatory and possibly anti-cancer. Slows Alzheimer's progression.

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Green tea.

Anti-oxidant, anti-cancer and anti-Alzheimer's effects

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Molecular Hydrogen.

Great for cellular oxygenation and free radical repair





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Fish—for omega 3 oils.

The best sources (in order) are mackerel, herrings, sardines, tuna, lake trout, sturgeon, salmon, anchovies, bluefish, halibut, bass, rainbow trout.


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Tomatoes.

For alpha lipoic acid and lycopene




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Cruciferous vegetables.

(broccoli, cauliflower, cabbage, Brussels sprouts, kale) for vitamins, anti-oxidants and anti-carcinogens.


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Raw garlic and almonds.

May help reduce arterial plaques and lower homocysteine levels, lowering heart attack risk.

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Cannabidiol

Creates homeostasis and everyday stress resilience




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Vinegar.

At the beginning of a meal, tempers the body's subsequent spike in blood sugar in response to carbohydrates.


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Soy is a mixed blessing.

The phytoestrogens in soy products seem to protect against heart disease and some cancers. But there is a theory afloat that high consumption of soy may contribute to brain aging.



In closing, I hope this list of powerful DNA enhancing nutrients make it onto your shopping list! In return, it’ll protect you from the small daily chronic levels of stress we are exposed to everyday.

CHEERS! xo Love n’ Ligh, Kassandra

Hormonal Frustration? It Could Be Linked to Your Endocannabinoid System.

Hormonal Frustration? It Could Be Linked to Your Endocannabinoid System.

Do you feel like you used to have a lot more energy?

Maybe you could get a good night's sleep, or were more easy going and positive about life.

So what’s causing this and who says what stays and what goes?

Some of us figure we're getting old.

Sometimes, life’s journey is not entirely in our own hands. For example, maybe there was an life event that took something out of you - an illness, or a new baby. After that, you were never the same.

If you don't feel like yourself - if you feel depleted and can't catch up - it is very possible that not only your hormones are out of balance - but your endocannabinoid system which is the largest “endocrine” messenger system in the body - is what we’re now discovering that we need to address first to accurately control the hormone cascade. The ECS is striving to keep us naturally in balance!

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Understanding the LINK between hormones and your endocrine system.

It’s important to have a basic understanding of hormones themselves, the endocrine system, and the relationship between the two.

Hormones are essentially chemical messengers. They are involved in numerous bodily processes, including growth and development, metabolism and appetite, sexual function, reproduction, and mood.

How do cannabinoids affect your hormones?

Studies have shown that the endocannabinoid system is also involved in managing endocrine processes. It does so by activating receptors in the brain and body, which directly influence activity in endocrine glands like the thyroid, pineal, and pituitary glands.

Hence, by stimulating the endocannabinoid system, cannabinoids can directly affect hormone levels in the body.

What does a endocannabinoid deficiency look and feel like?

Depression, anxiety, mood swings, hair loss, mental fog are common symptoms of deficient or imbalanced hormones.

Estrogen, progesterone and testosterone (the main female and male hormones) have powerful effects on the brain and the body.

Thyroid hormone is a key regulator of body and mind, and low thyroid function is more common than conventional tests can show.

If your adrenal glands are not healthy, you will have many emotional and mental symptoms in addition to body discomforts.

And low or high neurotransmitters such as serotonin and dopamine cause fatigue, anxiety and depression.

OK, enough doom and gloom! That’s not who we are, or called to be.

As women, we may want to just “treat our hormones” to feel better - there’s actually deeper story here. Studies are now discovering our endocannabinoid system MUST be in good working order for a healthy - HORMONES, body, mood, hair growth, …. You name it.

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So in closing, with the recent recognition of the critical and complex bidirectional effects of the endocannabinoid system and the dominant female hormone – estradiol – we have entered a new era, a new future filled with many potential opportunities both for the benefit and sometimes the detriment of women.

We must now begin our journey with the attainment of a solid knowledge-base of the endocannabinoid system, and an understanding of its complex role in reproductive, emotional, and immune health in women.


I’m beyond passionate in providing in-depth education for women, to enable them to assess their risk of both the potential for good and for harm from their contraceptive choices, pharmaceuticals used, exposures to endocrine disruptors, and equip them with the ability to make good decisions regarding their use of both CBD and medicinal cannabis.

Cheers to the journey of discovering more about the symphony of our endocannabinoid system and the interplay of these systems and of their implications for mental, hormonal and emotional wellbeing.

If you’d like to hop onto premium clinical grade CBD - curated for potency, bioavailability and fast healing - head on over to the EVOQ SHOP.

Want to learn all about your stress hormones, cannabinoids (CBD) with women and for women only?

Tap Below.

PS: Don’t forget, we host WOMEN and CBD EVENTS every last Sunday of the month so you can have a seat at the round table and learn more about your endocannabinoid system.


xo Love n’ Light - Kassandra

Why CBD Oil Is Becoming a Key Factor to Support Exercise Recovery

Why CBD Oil will become a Key Factor
to Exercise Recovery

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CBD FOR PAIN AND INFLAMMATION

  • Cannabinoids such as cannabidiol (CBD) have been proven to possess antioxidant and anti-inflammatory properties.

  • CBD is an analgesic, helping to alleviate pain both during and after exercise.

  • CBD has been shown to increase levels of the neurotransmitter (chemical messenger) anandamide – the main cannabinoid that is produced by the human body. By increasing activation of endocannabinoid receptors, anandamide can reduce pain and inflammation.

  • CBD also increases levels of adenosine as well – another neurotransmitter that appears to reduce inflammation. Rich in active cannabinoids can supercharge your recovery.

Superior Antioxidant Support

  • CBD outshines vitamin C and E as an antioxidant, protecting cells against the damage that reactive oxygen molecules cause.

CBD FOR SLEEP RECOVERY

  • CBD has the ability to reduce anxiety, research shows it can be a helpful component in improving sleep quality and reducing insomnia.

  • CBD has also been shown to reduce insomnia in people who suffer from chronic pain due to it’s anti-inflammatory properties.

  • CBD stimulates alertness and reduces daytime drowsiness, which is important for daytime performance and for the strength/consistency of the sleep-wake cycle.

Tincture Drops Dosage

  1. A standard starting dose is can start as low as 5-10 mg taken twice daily 12 hours apart and at least an hour and a half before or after any pharmaceuticals.

  2. Immediately post-workout is a great time for a dose. Try this for about 14 days.

  3. If no change occurs within 2 weeks, double the dose and hold that same dose for 3 weeks. Making notes of any change or relief can help you better understand your progress.

  4. If during this three week span relief is noticed, continue with that same dose for a full three weeks. Then, increase the dose based on how you feel.

  5. If you sense no major changes, I suggest dosing 15 drops of Evoq’s Tincture every evening for sustaining a healthy endocannabinoid tone and support for oxidative stress and neuroregenerative benefits. Science proves this.

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OVERVIEW OF CBD’S POST-WORKOUT BENEFITS

CBD holds various potential benefits for post-workout and everyday stress recovery:

  • Improved recovery, especially in cases of injury

  • Reduction of inflammation and pain – a common occurrence after hard training

  • Reduction of muscle spasms

  • Improved sleep

  • Neural Pathway health - cell to cell communication

Video and quote on the brain, science and CBD.


“ So, the targets of how cannabis works and an intrinsic set of neuromodulators called endocannabinoids that are released by cells and act at the receptors. So, although the system is distributed throughout the body, I tend to think about the brain and it’s very highly utilized by the brain.

And, as an example of how the brain works with endocannabinoids, a given neuron – a cell within the brain receiving thousands of different inputs – will release endocannabinoids, these small signaling molecules, to fine-tune the strength of their own synaptic inputs.

So the endocannabinoids are signaling molecules that are created and broken down by enzymes in the body.

They act at cell surface receptors that change the activity of cells. And all of this – the signaling molecules, the enzymes that make them and break them down, the receptors that exert the effects of the compounds – are bundled up into what we call the endocannabinoid system.”

www.evoqbeauty.com | Clean, Calm and Connected Organic Tinctures


Building Resilience with Herbal Allies to Support Women and Modern Day Mounting Stress

Hey Beaute’ - thanks for joining me!

kassandra

When we take small moments and care for ourselves, we get relief from not beating ourselves up for some past transgression or feeling anxious about meeting future expectations.

We get free to experience contentment and to make authentic connections with others and with our world.

Self love looks different for every woman and far from a one-size-fits-all silver bullet.

One thing I DO KNOW, plant medicinals can make all the difference.

HENCE, I’m sure you’ve been aware of the onslaught of CBD companies on the market.

This wonderful herbal allie can get to the root of a myriad of issues and is becoming a widely available and particularly soothing phyto-friend.

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CBD has exploded (and sometimes exploited) in popularity recently and for good reason: not only has it aided so many in managing their disharmonies, diseases, and symptoms, it has provided a held space, a calm center, from which to heal ourselves, from which to love ourselves.

How?
Plant medicine works directly with our endogenous endocannabinoid system (ECS) to down-regulate inflammation, moderate immune response, and maintain overall homeostasis in the body.

Homeostasis is the state of balance and equilibrium our bodies are always striving for, always fine tuning to achieve.

Excessive stress, poor nutrition, and exposure to environmental toxins makes this process more difficult. (PMS, hot flashes, anxiety attack, weight gain, etc).

Much of our trauma, overwhelm, and feelings of frustration or inadequacy manifests somatically, in the body, and CBD helps to unwind some of that tension so we can more effectively find our unique homeostasis.

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As stated, there’s no silver bullet, and it’s hard to know how to start, who to trust and how to even read a ingredient label If you find yourself lost on your unique path, then I have something in store for you!

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Learning about the various cannabinoids interactions within our body has taken me painstacken HOURS and over 2 years to fully comprehend. From how to find the best (truly organic) sources, how it works within our biochemistry, and helping consumer take their blind-folds off to see who’s in it just for the money.

It’s proven itself by helping both myself and hundreds of women I’ve coached using our pharmaceutical grade CBD - to discover and uncover ways in which to love ourselves and get back in a circadian sync - less anxiety, more sleep, reduced pain and more.

SO THIS IS THE ONLY NEXT STEP. 

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I’m beyond excited! (huge grin over here) To make this happen, I’m going BIG and I’m co-creating a space with the women of Ellementa, the fastest growing Women’s Cannabis Network in the nation as their MN Team Lead (your guide if I may).

This year's mission and events, with the theme of "Advancing Women’s Health and Cannabinoid Knowledge", will launch on March 31st as our first cutting-edge event - exclusive to WOMEN ONLY!

It's an honor to take Ellementa's mission and bring it to MN!

I’ll share more in my next post - so stay tuned! Can’t wait?

I’ll scoot you over to a good ol’ PRESS RELEASE right HERE!

&

JOIN our EXCLUSIVE FB GROUP to be notified of what’s to come!

I’ll see you soon - Love n’ Light - Kassandra

Is Hydrogen Water [H2] a Drink Never to Forget?

On the ongoing journey of being obsessed with CBD (cannabidiol) and how to assure the most bioavailable formulas for our customers, I discovered the recent up-roar around Molecular hydrogen (H₂).

Follow the fun and H2 education on the GRAM & WATCH the youtube video to this article below!

“What is so novel about HYDROGEN?” Let’s dive in and discover this unique molecular structure.

Simply put, molecular hydrogen acts as a powerful antioxidant.

Consider hydrogen molecules as the nice police force, helping us fight free radicals as we go about our day.


H2 Water

IN DEPTH

Molecular hydrogen (H₂) is the ultimate antioxidant. H₂ is known to eliminate only the most harmful free radicals, and may reduce oxidative stress to better help put our body in balance.

H2 gas is the smallest neutrally charged molecule on earth, giving it free range to instantly cross your cell membranes and the blood-brain barrier, and possibly further allowing it to access DNA and mitochondria within the cell where it has protective action.

The Free Radical Theory of Aging

The Free Radical Theory of Aging holds that the damage free radicals do to our cells, particularly the oxidative stress that free radicals cause, is what causes our bodies to age.

How H₂ Works

Size

Molecular hydrogen is the smallest molecule and the only antioxidant that can access the mitochondria and cell nucleus under certain conditions. Unlike most larger antioxidants, H₂ instantly passes through the cell membrane that may allow immediate benefits.

Non Toxic & 100% Safe

Molecular hydrogens byproduct is water, therefore you cannot overdose nor store in adipose (fatty) tissue.

Homeostasis

H₂ supports the body’s ability to maintain a condition of balance by neutralizing harmful free radicals while also boosting your own internal antioxidant system. This keeps oxidative stress low, supports homeostasis and decreases chance of disharmony.


Can we consume TOO MUCH antioxidant content?

YES, and of certain kinds. There’s been studies that correlate TOO MUCH of a consumption of antioxidants can desensitize the bodies innate defence system. It’s much like the Omega studies that reveal our nation is over-consuming Omega 6 in comparison to omega 3, in which increases inflammation.

Selectivity

H₂ target the harmful free radicals without affecting useful free radicals that sustain inner homeostasis. The concern is that we’re “over doing antioxidants common known as Vitamin A, C, E, folic acid, etc),” which can diminish the good free radicals that the body needs.  H₂ does not.

So as you go on and take your supplements, eat more berries, drink tea, or a glass of wine each night with the idea you intake all the antioxidants you need ….. please STOP and read because there’s a NEW SHERIFF is in town - and now found at Beauty Ecology.


A Free Radical Recap

Free radicals are uncharged or unstable molecules, which make them highly reactive and extremely likely that they’ll pull apart pieces of other molecules to gain stability. In their search for stability, they can damage your body.

H₂ to the Rescue!

So, why am I hooked? When a close Functional Medicine friend of mine threw H2 at me, my eyebrows raised. I was initially skeptical because hydrogen is so abundant, why had we not realized the power of this element before?

With over 1000 clinical studies (for cripes sake), it’s CLEAR this powerful molecule may have potential to contribute to multiple forms of symptoms such as:

*ridding oxidative stress, *better metabolism, *combating brain inflammation, *exercise recovery, *increased energy, *gut healing, *skin clarity, *anti-cancer and more.


THE 15 GAME CHANGING BENEFITS OF MOLECULAR HYDROGEN

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Pretty amazing, right?

Stick around and learn more about how these drops of effervescence may be the single, easiest way to introduce a hydrating “well of youth” to improve our inner health and outer beauty.

Take the Free Radical Aging Theory facts and do something about it today.





Resources:

https://www.ncbi.nlm.nih.gov/pubmed/11510417
https://www.ncbi.nlm.nih.gov/pubmed/23031079
https://www.ncbi.nlm.nih.gov/pubmed/26866650
https://www.ncbi.nlm.nih.gov/pubmed/22520831
https://www.ncbi.nlm.nih.gov/pubmed/24392771
https://www.ncbi.nlm.nih.gov/pubmed/21512236
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4865993/
https://www.ncbi.nlm.nih.gov/pubmed/21293445 https://www.nature.com/articles/nm1577
https://www.ncbi.nlm.nih.gov/pubmed/26276082

Is Cannabis (CBD) Safe with Other Medications?

Are you currently thinking about taking CBD, but too nervous to because you're on a medication?   This subject matter comes up a lot, so I thought I'd break it down quickly to bring clarity to the nuances of CBD and drug interactions. 

Cannabidiol (CBD) is one of over 80 phytocannabinoids, or chemical compounds, produced by the cannabis plant.  Starting off, Cannabidiol (CBD) itself has no dangerous interactions with other drugs you may be taking.

The breakdown of CBD and Drug interactions is all in the PATHWAY.

How?   Lets dig in!

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Just How Safe is CBD Oil?

Hemp’s cannabidiol continues to be one of the safest alternative therapies on the market. In a review published in 2017, entitled “An Update on Safety and Side Effects of Cannabidiol,” a Clinical Data author asserted: "In general CBD is the most commonly reported side effects that are relatively rare and mild.   

Comparably to the laundry list of drug symptoms - CBD has a short list of that few experience such as feeling tired or changes in appetite. Everyone has various levels of sensitivities, let alone the importance of making sure you’re buying high quality CBD!

How Does Your Body Metabolize CBD?

It’s important to understand how the human body processes CBD.   Essentially, our body breaks CBD down through metabolization, just like other oral drugs by entering the digestive tract.  Here, they absorbs through the stomach lining into the hepatic portal system. This system is a vital system of veins connecting the stomach to the liver, and also acts as one of the body’s filter systems.

Once CBD enters the liver, it soaks up the P450 enzyme processing capability, inhibiting its ability to break down any other hepatically metabolized drugs. The cytochrome P450-complex enzyme becomes entirely preoccupied with processing CBD, with little to no room to break down other compounds also awaiting metabolization.

While the P450 enzyme interact with CBD, the body virtually stops processing any other pharmaceuticals with the same metabolic pathway. Interestingly, it's not the only P450 inhibitor to worry about.

Grapefruit Too?

Yup, something as natural and nourishing as a grapefruit comes with a similar warning about possible drug interaction. Physicians have long advised their patients to steer clear of grapefruit when taking certain medications.

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If you do wish to pursue CBD as a co-therapy to other drugs, consider seeking medical advice and adjust dosages of any medications only on the recommendation of a doctor.

On the FLIP side, there is also a positive benefit to CBD hemp oil interaction with the P450 enzyme. Once we can make it proven through more robust studies, patients may be able to reduce their dose of other medications if CBD substantially increases the expected potency.

What Drugs Could CBD Interact With?

All drugs mainly metabolized by the liver pose a risk for adverse CBD drug interaction. Considering that 60 percent of clinically prescribed medication is metabolized in the liver via the P450 enzyme, it's not feasible to list them all here. Some of the most common types of medications which may trigger CBD hemp oil interactions include:

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  • HIV Antivirals

  • Steroids

  • Benzodiazepines

  • Antihistamines

  • Calcium Channel Blockers

  • Fentanyl

  • Macrolide Antibiotics

 


Cannabidiol (CBD) itself has no dangerous interactions, but it may interact with other drugs you may be taking according to medical journals.   Here's a list of possible drug interactions.

Why Does CYP450 Matter?

In order to determine the appropriate dosages of medications, doctors make calculations using the average amount of time it takes for various drugs and medications to be processed through the cytochrome P450 system.

If only one drug is being processed, and the system is generally healthy, these averages provide accurate dosage information.

However, certain substances have the ability to affect processing times within this system, making drugs metabolize faster or slower than they would on their own.

Similarly, if the cytochrome P450 system is unhealthy due to problems with the liver or other pre-existing conditions, drugs may not metabolize as they should.

Caffeine and CBD

Caffeine is the world’s most famous and commonly consumed psychoactive drug. Who doesn’t ingest even a little from time to time?

CBD oil is rapidly gaining ground on coffee in terms of popularity and so it only makes sense that people would start combining the two.

As it turns out, the two substances go very well together!

Caffeine is molecularly very similar to adenosine, a compound produced in our bodies that activates the A2a receptor. Caffeine binds to the A2a receptors, inhibiting the reuptake of adenosine.

When adenosine binds to the A2a receptor, the result is what is commonly known as the ‘rest and digest’ effect. Consequently, blocking adenosine from binding results in vasodilation, which increases clarity and alertness.

CBD oil is also a partial agonist of the A2a receptor; so the theory goes that by combining caffeine and CBD, adenosine is blocked across the board, resulting in not only more stimulation, but reduced anxiety (due to CBD’s effects on other neurotransmitters systems).

It is worth noting that these effects depend on the serving size of the CBD. High amounts of CBD are more likely to cause drowsiness and sedation.

Additionally, caffeine is metabolized by a CYP450 enzyme, specifically CYP1A2. As CBD inhibits the CYP450 enzyme system, a slowed excretion rate of caffeine will occur. This can mean the effects of the caffeine will be more prolonged and drawn out. The can be both good and bad!

On the bright side, CBD oil and caffeine together will cause the boost from your morning cup of coffee to last all day instead of just a few hours. On the downside, it’s easy to overdo it and end up wide-eyed in bed when you are trying to go to sleep.

Considering this information, again, it is best to be mindful and cautious when mixing caffeine and CBD.

Can CBD Oil Be Addictive?

One of the most common questions we get is: Can I get addicted to CBD oil? The answer depends on what you mean by “addicted.”

When looking at the chemical impacts of CBD oil, the answer is no. Cannabidiol is not physically addictive in the same way opiates, cocaine, alcohol, and other drugs can be. Also, CBD oil does not produce any physical withdrawal symptoms when you stop using it. In fact, CBD oil is currently being researched as a potential tool for minimizing the severe withdrawal from drugs like opiates.

But, having said that, human beings can get addicted to just about anything including exercise, music, sex, and food.

Because CBD oil can alter essential liver enzymes, it is crucial to do your research, talk to your physician, and figure out how to best consume CBD oil for your specific situation.

Information and education will be your most powerful weapons going forward.

How To Use CBD Oil

When taking cannabidiol, it is important to consume only the recommended serving size.  

Raising or lowering this amount may produce the opposite of the desired effect.

Keep in mind that some people may metabolize cannabidiol differently because of anomalies within the cytochrome P45O (CYP450) enzyme system. And depending on when you take your medications, you may find an unintended increase or decrease in CBD concentrations in your blood.

If you suspect that you are not metabolizing CBD oil as expected, ask your doctor to test your cytochrome P450 enzyme system before adjusting your dosage.

Resource:https://cbdoilreview.org/cbd-cannabidiol/cbd-p-450-enzyme/

Let’s review again.  Simply put…

When taking a dose of CBD, your body’s P450 enzymes will be temporarily inactive.   When enzymes are inactive, it becomes much harder for your body to process almost every drug out there.

This means:

Taking lots of CBD may increase the effects of any prescriptions drugs on your body. As they cannot be processed, the drugs will just stay in your body instead of being digested as they should.

The Good & Bad

The good side is that there may be a possibility reduce the amount of powerful prescription medications you take (speak to your physician before beginning or stopping medication). Regardless of what you take, it’s always best to put less artificial drugs into your body.

The bad side is just that you need to be careful. If you are taking CBD make sure to talk to a medical professional, and reduce the amount of prescription drugs you are taking.

So if you’re uber nervous, before adjusting any current prescriptions, or deciding to use CBD in conjunction with other drugs, always speak to a qualified medical professional.

From experience, many of my clients have been able to significantly lower the dosages of drugs they are using for a variety of ailments and symptoms.  This is the entire reason why CBD can benefit many - with the hope of reducing our use of drugs for everything from anxiety, insomnia, pain and headaches.

Making sure you’re purchasing very high quality CBD is a WHOLE OTHER SUBJECT.

Till next time!  Email me with any questions or concerns!  Hello@beautyecology.com

EVOQ CBD CURING CONCENTRATES

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